Evidence-based Health Care Special Lecture I

[http://minato.sip21c.org/ebhc.html] Latest update: 30-August-2013 (Fri)

Archives: 2012

1. Aims of the lecture

For properly conducting health related research, basic knowledge of research design and statistics will be given.

In principle, the lecture is done in Japanese. Foreign students may ask the lecturer individually if necessary.

Handouts for 2013 has summarized as a text (in Japanese) pdf, it's freely available.

2. Program

The very basics of health research (Apr 10, ref)
Basic terms in health/epidemiologic research (Apr 17, ref, ref in Japanese, mini-report form Note: The odds ratio calculation of this was impossible. Sorry.).
Sample size issues (Apr 24, handout, in Japanese)
Experimental study design (May 1, Handout (in Japanese), Homework until 9 June, data for the homework in Excel format¡¤data for the homework in tab-demilited text format)
Hypothesis testing, SD and SE (May 8, Handout in Japanese, see pp.8-19 of Text in the lecture at Gunma Univ. in 2012)
Basic Manipulation of Quantitative Data (May 22, Handout)
Correlation and Regression (May 29, Handout in 2012, in English, Handout in 2013, in Japanese)
ANOVA and multiple comparison (June 5, Handout in English, Handout in Japanese, sample data for Dunnett)
Repeated measurement: Comparison of location parameters among 3 or more groups with corresponding data (June 12, handout (pdf), ogtt01.txt, ogtt02.txt, hypno-psycho01.txt, sbp01.txt)
Evaluation of performances of diagnostic testing: ROC, Kappa statistics, and Bland-Altman plot (June 19, handout [Note: revised after the lecture], sample data)
EBHC and clinical examination: how to read the clinical examination data and evidences for its effective application. (June 26, given by Assoc. Prof. Taku Shirakawa)
EBHC and genetic information: evidences to involve genetic information into health science and clinical medicine. (July 3, given by Assoc. Prof. Taku Shirakawa)
Geographic Information Data Analysis (July 10, Special Lecture given by Dr. Susumu Tanimura)
Method to summarize systematic review: meta-analysis (July 17, handout, Pearson1.txt, Examples of meta-analysis: the case of global sperm decline issues: The paper given by Carlsen et al. 1992, Re-analysis for the essentially same data by Swan et al. 1997, Re-analysis with many newer papers by Swan et al. 2000, Recent critics by Deonandan and Jaleel, 2012, Data used by Carlsen et al. 1992, R code to plot the Carlsen et al.'s data)
Final mini-test (July 24, Questions and Possible Answers)

3. Evaluation

Based on the reports and discussion as a whole.

References

Machin D, Campbell MJ, Walters SJ (2007) Medical Statistics, 4th ed., Wiley
Lang TA, Secic M (2006) How to report statistics in medicine: Annotated guidelines for authors, editors, and reviewers. 2nd ed., American College of Physicians.
Peacock JL, Peacock PJ (2011) Oxford handbook of medical statistics. Oxford Univ. Press
Power and Sample Size (Vanderbilt University)
EZR (Jichi Medical School)
The lecture note for medical statistics at Gunma University written by Minato Nakazawa

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